BDBM625273 (-)-2-(4-fluorophenyl)-N-{4-[3-(4-fluorophenyl)-5-methyl-4-oxo-4,5-dihydro-1H-pyrrolo[3,2-c]pyridin-2-yl]pyridin-2-yl}propanamide (Enantiomer 1)::US20230322767, Example 101

SMILES CC(C(=O)Nc1cc(ccn1)-c1[nH]c2ccn(C)c(=O)c2c1-c1ccc(F)cc1)c1ccc(F)cc1

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 625273   

TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625273((-)-2-(4-fluorophenyl)-N-{4-[3-(4-fluorophenyl)-5-...)
Affinity DataIC50:  12nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625273((-)-2-(4-fluorophenyl)-N-{4-[3-(4-fluorophenyl)-5-...)
Affinity DataIC50:  32.4nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into either a black low volume 384 well microtiter ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetcsnk1d(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625273((-)-2-(4-fluorophenyl)-N-{4-[3-(4-fluorophenyl)-5-...)
Affinity DataIC50:  5.60nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1D, expressed by baculovirus infected insect cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent