BDBM625305 N-{4-[3-(5-chloro-2-thienyl)-5-methyl-4-oxo-4,5-dihydro-1H-pyrrolo[3,2-c]pyridin-2-yl]pyridin-2-yl}-4,4-difluoro-2-(4-fluorophenyl)butanamide (Racemate)::US20230322767, Example 133

SMILES Cn1ccc2[nH]c(c(-c3ccc(Cl)s3)c2c1=O)-c1ccnc(NC(=O)C(CC(F)F)c2ccc(F)cc2)c1

InChI Key InChIKey=RYHVMNZCJGRAGW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 625305   

TargetCasein kinase I isoform alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625305(US20230322767, Example 133 | N-{4-[3-(5-chloro-2-t...)
Affinity DataIC50: 2.30nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetCasein kinase I isoform delta(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625305(US20230322767, Example 133 | N-{4-[3-(5-chloro-2-t...)
Affinity DataIC50: 4.80nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1D, expressed by baculovirus infected insect cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625305(US20230322767, Example 133 | N-{4-[3-(5-chloro-2-t...)
Affinity DataIC50: 2.00E+4nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into either a black low volume 384 well microtiter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent