BDBM627187 N-[(3S)-3-cyanotetrahydrofuran-3- yl]-3-[3-(difluoromethoxy)phenyl]-1- isopropyl-pyrazolo[4,3-b]pyridine-6- carboxamide::US11787810, Example 38

SMILES CC(C)n1nc(-c2cccc(OC(F)F)c2)c2ncc(cc12)C(=O)N[C@@]1(CCOC1)C#N

InChI Key InChIKey=UYIZJBRGHIEPKV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 627187   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM627187(N-[(3S)-3-cyanotetrahydrofuran-3- yl]-3-[3-(difluo...)
Affinity DataIC50: 11nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
US Patent