BDBM627210 N-(3,3-difluoro-1- (hydroxymethyl)cyclobutyl)-3-(3- (difluoromethoxy)phenyl)-1- isopropyl-1H-pyrazolo[4,3- b]pyridine-6-carboxamide::US11787810, Example 51

SMILES CC(C)n1nc(-c2cccc(OC(F)F)c2)c2ncc(cc12)C(=O)NC1(CO)CC(F)(F)C1

InChI Key InChIKey=XGKWDMPULHLMDO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 627210   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM627210(N-(3,3-difluoro-1- (hydroxymethyl)cyclobutyl)-3-(3...)
Affinity DataIC50: 17nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
US Patent