BDBM627214 3-(5-(difluoromethoxy)pyridin-3-yl)- N-((2S,3S)-2-hydroxy-4- methylpentan-3-yl)-1-isopropyl-1H- pyrazolo[4,3-b]pyridine-6- carboxamide::US11787810, Example 54

SMILES CC(C)[C@H](NC(=O)c1cnc2c(nn(C(C)C)c2c1)-c1cncc(OC(F)F)c1)[C@H](C)O

InChI Key InChIKey=NBKQKGDZGFMZIV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 627214   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM627214(3-(5-(difluoromethoxy)pyridin-3-yl)- N-((2S,3S)-2-...)
Affinity DataIC50: 13nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
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Date in BDB:
11/29/2023
Entry Details
US Patent