BDBM627217 3-(2-ethoxy-5-fluoropyridin-4-yl)-N- ((1S,2R)-2-hydroxy-1- methylcyclopentyl)-1-isopropyl-1H- pyrazolo[4,3-b]pyridine-6- carboxamide::US11787810, Example 57

SMILES CCOc1cc(-c2nn(C(C)C)c3cc(cnc23)C(=O)N[C@@]2(C)CCC[C@H]2O)c(F)cn1

InChI Key InChIKey=SCNIXPKMVWMKBW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 627217   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM627217(3-(2-ethoxy-5-fluoropyridin-4-yl)-N- ((1S,2R)-2-hy...)
Affinity DataIC50: 15nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
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Date in BDB:
11/29/2023
Entry Details
US Patent