BDBM633263 US20190276450, Example 1.2
SMILES CO[C@]1(CCOC1)c1cccc(n1)-c1cn([C@@H]2CC2(F)F)c2cnc(NC(N)=O)cc12
InChI Key InChIKey=XISLDXFCWSBFQH-XLIONFOSSA-N
Data 3 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 633263
Affinity DataEC50: 45nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
Affinity DataEC50: >2.50E+4nMAssay Description:Erythropoietin (EPO) is known to transduce its signal through EPO receptor via Jak2. Activity against Jak2 was therefore measured by determining inhi...More data for this Ligand-Target Pair
Affinity DataEC50: 1.35E+4nMAssay Description:IL-6 is known to transduce its signal through IL-6 receptor via Jak1. Activity against Jak was therefore measured by determining inhibition of IL-6 i...More data for this Ligand-Target Pair