BDBM636590 (S)-5-((3-hydroxypyrrolidin- 1-yl)methyl)-1-(1H-pyrazol-4-yl)- 4,6,7,8-tetrahydro-3H-9-oxa-2-thia-4- azabenzo[cd]azulen-3-one::US20230365584, Compound 11.

SMILES O=c1[nH]c(CN2CC[C@H](O)C2)c2c3c(c(-c4cn[nH]c4)sc13)OCCC2

InChI Key InChIKey=ISKJWFOCLMMCEM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 636590   

TargetCell division cycle 7-related protein kinase(Human)
SchrÖDinger

US Patent
LigandChemical structure of BindingDB Monomer ID 636590BDBM636590((S)-5-((3-hydroxypyrrolidin- 1-yl)methyl)-1-(1H-py...)
Affinity DataIC50: 1nMAssay Description:Full length human CDC7 protein co-expressed with DBF4 was purchased from SignalChem (China). CDC7 kinase activity was determined with PDKtide (Signal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
US Patent