BDBM638731 US20230390287, ID 45

SMILES COc1ccc(cc1)-c1nc(N)nc(c1Cl)-c1cc(C)ccc1O

InChI Key InChIKey=JKPCNFGIHMUCNW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 638731   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Wenzhou Medical University Lishui Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 638731BDBM638731(US20230390287, ID 45)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human PD-1/PD-L1 incubated for 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Wenzhou Medical University Lishui Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 638731BDBM638731(US20230390287, ID 45)
Affinity DataIC50: 596nMAssay Description:The identified compounds were tested for their capacity to inhibit the PD-1/PD-L1 interaction using in vitro functional assays. Homogeneous time reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent