BDBM638737 US20230390287, ID 84

SMILES Cc1nc(C)c(cc1C(=O)NNC(=O)Cc1ccccc1)C(=O)NNC(=O)Cc1ccccc1

InChI Key InChIKey=YUGDLITYLAUWLD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 638737   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Wenzhou Medical University Lishui Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 638737BDBM638737(US20230390287, ID 84)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human PD-1/PD-L1 incubated for 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Wenzhou Medical University Lishui Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 638737BDBM638737(US20230390287, ID 84)
Affinity DataIC50: 1.09E+3nMAssay Description:The identified compounds were tested for their capacity to inhibit the PD-1/PD-L1 interaction using in vitro functional assays. Homogeneous time reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent