BDBM682025 N-Cyclopropyl-3-(5-(6-(2,3- dihydroxypropoxy)-1H-indole- 3-carbonyl)pyridin-2-yl)-5- fluoro-4-methylbenzamide::US20240270713, Compound 3

SMILES Cc1c(F)cc(cc1-c1ccc(cn1)C(=O)c1c[nH]c2cc(OCC(O)CO)ccc12)C(=O)NC1CC1

InChI Key InChIKey=BRTWKUIKLIEJRW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 682025   

TargetMitogen-activated protein kinase 11(Human)
Prazertherapeutics

US Patent
LigandPNGBDBM682025(N-Cyclopropyl-3-(5-(6-(2,3- dihydroxypropoxy)-1H-i...)
Affinity DataIC50: 34.3nMAssay Description:Briefly, the compounds were diluted at concentrations of 1000, 333, 111, 37.0, 12.3, 4.12, 1.37, 0.457, 0.152, and 0.0495 nM, respectively, and then ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent