BDBM682121 8-(6-((2-(3,3- dimethylpyrrolidin-1- yl)ethoxy)methyl)pyridin-3- yl)-7-fluoro-1-isopropyl-3- methyl-1H-imidazo[4,5- c]cinnolin-2(3H)-one::US20240207263, Example 60

SMILES CC(C)n1c2c(nnc3ccc(cc23)-c2ccc(nc2)[C@@H](C)OCCN2CCC(C2)OC(F)(F)F)n(C)c1=O

InChI Key InChIKey=JYKMUBCRJCHBCK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 682121   

TargetSerine-protein kinase ATM(Human)
Suzhou Zanrong Pharma

US Patent
LigandPNGBDBM682121(8-(6-((2-(3,3- dimethylpyrrolidin-1- yl)ethoxy)met...)
Affinity DataIC50: 2.80nMAssay Description:ATM (Millipore, Cat. No. 14-933) enzyme solution was prepared in 1x kinase base buffer. 10 ul of 2x enzyme solution was transferred to each well of t...More data for this Ligand-Target Pair
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Date in BDB:
10/4/2024
Entry Details
US Patent