BDBM682142 (R)-1-isopropyl-3-methyl-8- (6-(1-(2-(4-(oxetan-3- yl)piperidin-1- yl)ethoxy)ethyl)pyridin-3-yl)- 1H-imidazo[4,5-c]cinnolin- 2(3H)-one::US20240207263, Example 83

SMILES CC(C)n1c2c(nnc3ccc(cc23)-c2ccc(nc2)[C@@H](C)OCCN2CCC(CC2)C2COC2)n(C)c1=O

InChI Key InChIKey=XULFHBGJRAWUMO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 682142   

TargetSerine-protein kinase ATM(Human)
Suzhou Zanrong Pharma

US Patent
LigandPNGBDBM682142(US20240207263, Example 83 | (R)-1-isopropyl-3-meth...)
Affinity DataIC50: 2.40nMAssay Description:ATM (Millipore, Cat. No. 14-933) enzyme solution was prepared in 1x kinase base buffer. 10 ul of 2x enzyme solution was transferred to each well of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent