BDBM682144 1-isopropyl-8-(6-((R)-1-(2- ((R)-3- (methoxymethyl)pyrrolidin- 1-yl)ethoxy)ethyl)pyridin-3- yl)-3-methyl-1H-imidazo[4,5- c]cinnolin-2(3H)-one::US20240207263, Example 85

SMILES COC[C@@H]1CCN(CCO[C@H](C)c2ccc(cn2)-c2ccc3nnc4n(C)c(=O)n(C(C)C)c4c3c2)C1

InChI Key InChIKey=UXXXPTZRUCYXMQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 682144   

TargetSerine-protein kinase ATM(Human)
Suzhou Zanrong Pharma

US Patent
LigandPNGBDBM682144(US20240207263, Example 85 | 1-isopropyl-8-(6-((R)-...)
Affinity DataIC50: 3.40nMAssay Description:ATM (Millipore, Cat. No. 14-933) enzyme solution was prepared in 1x kinase base buffer. 10 ul of 2x enzyme solution was transferred to each well of t...More data for this Ligand-Target Pair
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Date in BDB:
10/4/2024
Entry Details
US Patent