BDBM682150 (R)-8-(6-(1-(2-(4- isopropoxypiperidin-1- yl)ethoxy)ethyl)pyridin-3-yl)- 1-isopropyl-3-methyl-1H- imidazo[4,5-c]cinnolin- 2(3H)-one::US20240207263, Example 92

SMILES CC(C)OC1CCN(CCO[C@H](C)c2ccc(cn2)-c2ccc3nnc4n(C)c(=O)n(C(C)C)c4c3c2)CC1

InChI Key InChIKey=ZTCAFYJFCAFKCX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 682150   

TargetSerine-protein kinase ATM(Human)
Suzhou Zanrong Pharma

US Patent
LigandPNGBDBM682150(US20240207263, Example 92 | (R)-8-(6-(1-(2-(4- iso...)
Affinity DataIC50: 1.5nMAssay Description:ATM (Millipore, Cat. No. 14-933) enzyme solution was prepared in 1x kinase base buffer. 10 ul of 2x enzyme solution was transferred to each well of t...More data for this Ligand-Target Pair
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Date in BDB:
10/4/2024
Entry Details
US Patent