BDBM682172 (R)-8-(6-(1-(2-(2-oxa-6-azaspiro[3.4]octan-6-yl)ethoxy)ethyl) pyridin-3-yl)-3-methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-imidazo[4,5-c]cinnolin-2(3H)-one::US20240207263, Example 116

SMILES C[C@@H](OCCN1CCC2(COC2)C1)c1cc2c3n(C4CCOCC4)c(=O)n(C)c3nnc2cn1

InChI Key InChIKey=PMOKIUNICZWDGE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 682172   

TargetSerine-protein kinase ATM(Human)
Suzhou Zanrong Pharma

US Patent
LigandPNGBDBM682172(US20240207263, Example 116 | (R)-8-(6-(1-(2-(2-oxa...)
Affinity DataIC50: 2.90nMAssay Description:ATM (Millipore, Cat. No. 14-933) enzyme solution was prepared in 1x kinase base buffer. 10 ul of 2x enzyme solution was transferred to each well of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent