BDBM682175 8-(6-((R)-1-(2-((R)-3- (methoxymethyl)pyrrolidin-1- yl)ethoxy)ethyl)pyridin-3-yl)- 3-methyl-1-(tetrahydro-2H- pyran-4-yl)-1H-imidazo[4,5- c]cinnolin-2(3H)-one::US20240207263, Example 119

SMILES COC[C@@H]1CCN(CCO[C@H](C)c2ccc(cn2)-c2ccc3nnc4n(C)c(=O)n(C5CCOCC5)c4c3c2)C1

InChI Key InChIKey=KWCKLBPRVBNUMA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 682175   

TargetSerine-protein kinase ATM(Human)
Suzhou Zanrong Pharma

US Patent
LigandPNGBDBM682175(US20240207263, Example 119 | 8-(6-((R)-1-(2-((R)-3...)
Affinity DataIC50: 2.40nMAssay Description:ATM (Millipore, Cat. No. 14-933) enzyme solution was prepared in 1x kinase base buffer. 10 ul of 2x enzyme solution was transferred to each well of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent