BDBM682180 (R)-8-(6-(1-(2-(7- azaspiro[3.5]nonan-7- yl)ethoxy)ethyl)pyridin-3-yl)- 3-methyl-1-(tetrahydro-2H- pyran-4-yl)-1H-imidazo[4,5- c]cinnolin-2(3H)-one::US20240207263, Example 124

SMILES C[C@@H](OCCN1CCC2(CCC2)CC1)c1ccc(cn1)-c1ccc2nnc3n(C)c(=O)n(C4CCOCC4)c3c2c1

InChI Key InChIKey=KMOZUEZUXLLRPD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 682180   

TargetSerine-protein kinase ATM(Human)
Suzhou Zanrong Pharma

US Patent
LigandPNGBDBM682180(US20240207263, Example 124 | (R)-8-(6-(1-(2-(7- az...)
Affinity DataIC50: 1.10nMAssay Description:ATM (Millipore, Cat. No. 14-933) enzyme solution was prepared in 1x kinase base buffer. 10 ul of 2x enzyme solution was transferred to each well of t...More data for this Ligand-Target Pair
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Date in BDB:
10/4/2024
Entry Details
US Patent