BDBM682184 (R)-3-methyl-8-(6-(1-(2-(4- (oxetan-3-yl)piperidin-1- yl)ethoxy)ethyl)pyridin-3-yl)- 1-(tetrahydro-2H-pyran-4-yl)- 1H-imidazo[4,5-c]cinnolin- 2(3H)-one::US20240207263, Example 128

SMILES C[C@@H](OCCN1CCC(CC1)C1COC1)c1ccc(cn1)-c1ccc2nnc3n(C)c(=O)n(C4CCOCC4)c3c2c1

InChI Key InChIKey=DPCIKWVAFVCNAO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 682184   

TargetSerine-protein kinase ATM(Human)
Suzhou Zanrong Pharma

US Patent
LigandPNGBDBM682184(US20240207263, Example 128 | (R)-3-methyl-8-(6-(1-...)
Affinity DataIC50: 4.60nMAssay Description:ATM (Millipore, Cat. No. 14-933) enzyme solution was prepared in 1x kinase base buffer. 10 ul of 2x enzyme solution was transferred to each well of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent