BDBM682193 (R)-8-(6-(1-(2-(4,4- dimethylpiperidin-1- yl)ethoxy)ethyl)pyridin-3-yl)- 7-fluoro-1-isopropyl-3- methyl-1H-imidazo[4,5- c]cinnolin-2(3H)-one::US20240207263, Example 139

SMILES CC(C)n1c2c(nnc3cc(F)c(cc23)-c2ccc(nc2)[C@@H](C)OCCN2CCC(C)(C)CC2)n(C)c1=O

InChI Key InChIKey=KXXCKUJAYVLAFJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 682193   

TargetSerine-protein kinase ATM(Human)
Suzhou Zanrong Pharma

US Patent
LigandPNGBDBM682193(US20240207263, Example 139 | (R)-8-(6-(1-(2-(4,4- ...)
Affinity DataIC50: 2.80nMAssay Description:ATM (Millipore, Cat. No. 14-933) enzyme solution was prepared in 1x kinase base buffer. 10 ul of 2x enzyme solution was transferred to each well of t...More data for this Ligand-Target Pair
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Date in BDB:
10/4/2024
Entry Details
US Patent