BDBM690177 5-(4-hydroxy-4-methylpiperidin-1-yl)-N-(2-methyl-5-(2-((1s,3s)-3-(trifluoromethyl)cyclobutyl)-2H-tetrazol-5-yl)phenyl)pyrazolo[1,5-a]pyridine-3-carboxamide or 5-(4-hydroxy-4-methylpiperidin-1-yl)-N-(2-methyl-5-(2-((1r,3r)-3-(trifluoromethyl)cyclobutyl)-2H-tetrazol-5-yl)phenyl)pyrazolo[1,5-a]pyridine-3-carboxamide::US20240262826, Compound 122

SMILES Cc1ccc(cc1NC(=O)c1cnn2ccc(cc12)N1CCC(C)(O)CC1)-c1nnn(n1)[C@H]1C[C@H](C1)C(F)(F)F

InChI Key InChIKey=IKWLXRDHRKYXBB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 690177   

TargetMast/stem cell growth factor receptor Kit(Human)
Blueprint Medicines

US Patent
LigandPNGBDBM690177(5-(4-hydroxy-4-methylpiperidin-1-yl)-N-(2-methyl-5...)
Affinity DataIC50: 0.600nMAssay Description:For the PathScan phospho c-kit (Tyr719) sandwich ELISA: M-07e cells were resuspended at 2×106 cells/mL in phenol red free, serum-free, GM-CSF-free Is...More data for this Ligand-Target Pair
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Date in BDB:
11/25/2024
Entry Details
US Patent