BDBM690290 N-(2-chloro-5-(2-cyclopropyl-2H-tetrazol-5-yl)phenyl)-5-(1-((4-hydroxytetrahydro-2H-pyran-4-yl)methyl)-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carboxamide::US20240262826, Compound 236

SMILES OC1(Cn2cc(cn2)-c2ccn3ncc(C(=O)Nc4cc(ccc4Cl)-c4nnn(n4)C4CC4)c3c2)CCOCC1

InChI Key InChIKey=HWUALMIYEFQUBW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 690290   

TargetMast/stem cell growth factor receptor Kit(Human)
Blueprint Medicines

US Patent
LigandPNGBDBM690290(N-(2-chloro-5-(2-cyclopropyl-2H-tetrazol-5-yl)phen...)
Affinity DataIC50: 0.600nMAssay Description:For the PathScan phospho c-kit (Tyr719) sandwich ELISA: M-07e cells were resuspended at 2×106 cells/mL in phenol red free, serum-free, GM-CSF-free Is...More data for this Ligand-Target Pair
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Date in BDB:
11/25/2024
Entry Details
US Patent