BDBM690302 (S)-N-(2-chloro-5-(2-cyclopropyl-2H-tetrazol-5-yl)phenyl)-5-(1-(2-hydroxy-3-methoxypropyl)-5-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carboxamide::US20240262826, Compound 248

SMILES COC[C@@H](O)Cn1ncc(c1C)-c1ccn2ncc(C(=O)Nc3cc(ccc3Cl)-c3nnn(n3)C3CC3)c2c1

InChI Key InChIKey=HSZUGVCBIWLHGM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 690302   

TargetMast/stem cell growth factor receptor Kit(Human)
Blueprint Medicines

US Patent
LigandPNGBDBM690302((S)-N-(2-chloro-5-(2-cyclopropyl-2H-tetrazol-5-yl)...)
Affinity DataIC50: 0.600nMAssay Description:For the PathScan phospho c-kit (Tyr719) sandwich ELISA: M-07e cells were resuspended at 2×106 cells/mL in phenol red free, serum-free, GM-CSF-free Is...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2024
Entry Details
US Patent