BDBM690314 N-(2-chloro-5-(2-cyclopropyl-2H-tetrazol-5-yl)-4-fluorophenyl)-5-(1-(2-hydroxy-2-methylpropyl)-3-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carboxamide::US20240262826, Compound 260

SMILES Cc1nn(CC(C)(C)O)cc1-c1ccc2c(cnn2c1)C(=O)Nc1cc(-c2nnn(n2)C2CC2)c(F)cc1Cl

InChI Key InChIKey=NBGUEMDZIYAZEX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 690314   

TargetMast/stem cell growth factor receptor Kit(Human)
Blueprint Medicines

US Patent
LigandPNGBDBM690314(N-(2-chloro-5-(2-cyclopropyl-2H-tetrazol-5-yl)-4-f...)
Affinity DataIC50: 0.600nMAssay Description:For the PathScan phospho c-kit (Tyr719) sandwich ELISA: M-07e cells were resuspended at 2×106 cells/mL in phenol red free, serum-free, GM-CSF-free Is...More data for this Ligand-Target Pair
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Date in BDB:
11/25/2024
Entry Details
US Patent