BDBM690318 (S)-N-(2-chloro-5-(2-cyclopropyl-2H-tetrazol-5-yl)-4-fluorophenyl)-5-(1-(2-hydroxypropyl)-5-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carboxamide::US20240262826, Compound 264

SMILES C[C@H](O)Cn1ncc(c1C)-c1ccn2ncc(C(=O)Nc3cc(-c4nnn(n4)C4CC4)c(F)cc3Cl)c2c1

InChI Key InChIKey=WRVGPCKEZSMLKC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 690318   

TargetMast/stem cell growth factor receptor Kit(Human)
Blueprint Medicines

US Patent
LigandPNGBDBM690318((S)-N-(2-chloro-5-(2-cyclopropyl-2H-tetrazol-5-yl)...)
Affinity DataIC50: 0.5nMAssay Description:For the PathScan phospho c-kit (Tyr719) sandwich ELISA: M-07e cells were resuspended at 2×106 cells/mL in phenol red free, serum-free, GM-CSF-free Is...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2024
Entry Details
US Patent