BDBM690331 N-(5-(5-cyclopropyl-2H-tetrazol-2-yl)-2-methylphenyl)-4-fluoro-6-(1-((4-hydroxytetrahydro-2H-pyran-4-yl)methyl)-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carboxamide::US20240262826, Compound 277

SMILES Cc1ccc(cc1NC(=O)c1cnn2cc(cc(F)c12)-c1cnn(CC2(O)CCOCC2)c1)-n1nnc(n1)C1CC1

InChI Key InChIKey=HWGNGCCGALMBIA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 690331   

TargetMast/stem cell growth factor receptor Kit(Human)
Blueprint Medicines

US Patent
LigandPNGBDBM690331(N-(5-(5-cyclopropyl-2H-tetrazol-2-yl)-2-methylphen...)
Affinity DataIC50: 0.5nMAssay Description:For the PathScan phospho c-kit (Tyr719) sandwich ELISA: M-07e cells were resuspended at 2×106 cells/mL in phenol red free, serum-free, GM-CSF-free Is...More data for this Ligand-Target Pair
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Date in BDB:
11/25/2024
Entry Details
US Patent