BDBM694447 US20240293400, Compound 3

SMILES CN1CCN(Cc2cccc(c2)-c2cnc3[nH]cc(-c4cc(NC(=O)Nc5ccccc5)ccc4F)c3c2)CC1

InChI Key InChIKey=WUPLDKYYIOASBT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 694447   

TargetTyrosine-protein kinase receptor UFO(Human)
Centre National de la Recherche Scientifique

US Patent
LigandPNGBDBM694447(US20240293400, Compound 3)
Affinity DataIC50: 6.30nMAssay Description:To calculate the IC50 inhibition of Axl and FLT3 by the compounds of the invention, 10 concentrations of each compound 1, 2 and 3 were prepared by 1/...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Centre National de la Recherche Scientifique

US Patent
LigandPNGBDBM694447(US20240293400, Compound 3)
Affinity DataIC50: 48.2nMAssay Description:To calculate the IC50 inhibition of Axl and FLT3 by the compounds of the invention, 10 concentrations of each compound 1, 2 and 3 were prepared by 1/...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent