BDBM719722 N-((5-(2-((6-(difluoromethyl)-1- methyl-1H-pyrazolo[3,4- d]pyrimidin-4- yl)thio)acetyl)thiophen-2- yl)methyl)pivalamide::US20250051319, Compound 21::US12421222, Compound 21
SMILES Cn1ncc2c(SCC(=O)c3ccc(CNC(=O)C(C)(C)C)s3)nc(C(F)F)nc21
InChI Key InChIKey=YSANBTZJSBXYQF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 719722
Affinity DataIC50: 100nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of HDAC enzymes was performed in 384-well plate format using human full-length recombinant HDAC1 and HDAC6, isolated from a baculovirus ex...More data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:NanoBRET target engagement was performed against the catalytic domain 2 (CD2) of HDAC6, with minor modifications of kit manufacturer protocol (Promeg...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair