BDBM719727 1-(2-(5-(2-((2- (trifluoromethyl)quinazolin-4- yl)thio)acetyl)thiophen-2- yl)ethyl)pyrrolidin-2-one::US20250051319, Compound 26::US12421222, Compound 26
SMILES O=C(CSc1nc(C(F)(F)F)nc2ccccc12)c1ccc(CCN2CCCC2=O)s1
InChI Key InChIKey=CXMSBGYLVQEFHD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 719727
Affinity DataIC50: 100nMAssay Description:Inhibition of HDAC enzymes was performed in 384-well plate format using human full-length recombinant HDAC1 and HDAC6, isolated from a baculovirus ex...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:NanoBRET target engagement was performed against the catalytic domain 2 (CD2) of HDAC6, with minor modifications of kit manufacturer protocol (Promeg...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair