BDBM719791 1-cyclopropyl-N-((5-(2-((2- methylquinazolin-4- yl)thio)acetyl)thiophen-2- yl)methyl)methanesulfonamide::US20250051319, Compound 93::US12421222, Compound 93
SMILES Cc1nc(SCC(=O)c2ccc(CNS(=O)(=O)CC3CC3)s2)c2ccccc2n1
InChI Key InChIKey=QMKJCOVIQIZWCK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 719791
Affinity DataIC50: 100nMAssay Description:Inhibition of HDAC enzymes was performed in 384-well plate format using human full-length recombinant HDAC1 and HDAC6, isolated from a baculovirus ex...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:NanoBRET target engagement was performed against the catalytic domain 2 (CD2) of HDAC6, with minor modifications of kit manufacturer protocol (Promeg...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair