BDBM719981 N-((5-(2-((1-methyl-1H- pyrazolo[3,4-d]pyrimidin-4- yl)thio)acetyl)thiophen-2- yl)methyl)-2-phenylacetamide::US20250051319, Compound 32::US12421222, Compound 32

SMILES Cn1ncc2c(SCC(=O)c3ccc(CNC(=O)Cc4ccccc4)s3)ncnc21

InChI Key InChIKey=NXGXGDCLZKVMSB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 719981   

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719981(N-((5-(2-((1-methyl-1H- pyrazolo[3,4-d]pyrimidin-4...)
Affinity DataIC50: 100nMAssay Description:Inhibition of HDAC enzymes was performed in 384-well plate format using human full-length recombinant HDAC1 and HDAC6, isolated from a baculovirus ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719981(N-((5-(2-((1-methyl-1H- pyrazolo[3,4-d]pyrimidin-4...)
Affinity DataIC50: 100nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719981(N-((5-(2-((1-methyl-1H- pyrazolo[3,4-d]pyrimidin-4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent