BDBM722096 US20250059174, Example 171-20

SMILES COc1nc(C)ccc1c6ccn5ncc(C(=O)Nc4cc(c3noc([C@H]2C[C@@H]2F)n3)ccc4C)c5c6

InChI Key InChIKey=AYLZZVHEOUGUSB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 722096   

TargetMast/stem cell growth factor receptor Kit(Human)
Enanta Pharmaceuticals

US Patent
LigandPNGBDBM722096(US20250059174, Example 171-20)
Affinity DataIC50: 100nMAssay Description:Kinase Reaction: The kinase assay was based on the recommended protocol by c-KIT Kinase Enzyme System from Promega. Recombinant human c-KIT kinase in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent