BDBM722731 N-(4-(2H-1,2,3-triazol-2-yl)-3-(trifluoromethyl)phenyl)-5-cyclopropyl-1-(2-oxo-1,2-dihydropyrrolo[4,3,2-ij]isoquinolin-6-yl)-1H-pyrazole-4-carboxamide::US20250059196, Example 83

SMILES O=C(Nc1ccc(-n2nccn2)c(C(F)(F)F)c1)c1cnn(-c2cnc3c4c(cccc24)C(=O)N3)c1C1CC1

InChI Key InChIKey=YGHUGPUKOPLXND-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 722731   

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM722731(N-(4-(2H-1,2,3-triazol-2-yl)-3-(trifluoromethyl)ph...)
Affinity DataIC50: 50nMAssay Description:1.1 Experimental PurposeAc-LRSR-AMC was used as the substrate to test the IC50 of the inhibitory activity of compounds on MALT1 enzyme activity at th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent