BDBM732122 US20250114361, Example 2

SMILES COc1cc(C)c(-n2cc3c(=O)[nH]c(-c4ccn(C)n4)nc3n2)c(C)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 732122   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Japan Tobacco

US Patent
LigandPNGBDBM732122(US20250114361, Example 2)
Affinity DataIC50: 64nMAssay Description:The NLRP3 inflammasome inhibitory activity of test compounds were evaluated on the basis of the inhibitory activity of the IL-1β production in THP1-N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent