BDBM732862 US20250115578, KH09::US20250115578, Example 09

SMILES NC(=O)c1cc(NC(=O)c2cc3ccccc3nc2N2CCCC(F)(F)CC2)ccc1F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 732862   

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical

US Patent
LigandPNGBDBM732862(US20250115578, KH09 | US20250115578, Example 09)
Affinity DataIC50: 0.918nMAssay Description:Clamped the cell at −80 mV and then depolarized to 10 mV with a square wave lasting 10 ms to get the Nav1.8 current (see FIG. 1 attached). This proce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical

US Patent
LigandPNGBDBM732862(US20250115578, KH09 | US20250115578, Example 09)
Affinity DataIC50: 1nMAssay Description:A capillary glass pipette (BF150-86-10, Sutter Instruments) was pulled into a recording electrode with a micropipette puller (P97, Sutter Instruments...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent