BDBM732872 2-(4,4-difluoroazepan-1-yl)-N-(2-(S-methylsulfonimidoyl)pyridin-4-yl)quinoline-3-carboxamide (KH26)::US20250115578, Example 26

SMILES CS(=N)(=O)c1cc(NC(=O)c2cc3ccccc3nc2N2CCCC(F)(F)CC2)ccn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 732872   

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM732872(2-(4,4-difluoroazepan-1-yl)-N-(2-(S-methylsulfonim...)
Affinity DataIC50: 8nMAssay Description:Clamped the cell at −80 mV and then depolarized to 10 mV with a square wave lasting 10 ms to get the Nav1.8 current (see FIG. 1 attached). This proce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent