BDBM738493 US20250145606, Example 52

SMILES Cc1ncc(C(=O)Nc2cc(C(=O)Nc3cccc(CC(F)(F)F)n3)c(F)cc2C)s1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 738493   

TargetMast/stem cell growth factor receptor Kit(Human)
Arcus Biosciences

US Patent
LigandPNGBDBM738493(US20250145606, Example 52)
Affinity DataIC50: 100nMAssay Description:On the day of the assay, compounds were solubilized in DMSO and dispensed into a 384-well white Opti-plate (PerkinElmer, catalog #6007290) to generat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Arcus Biosciences

US Patent
LigandPNGBDBM738493(US20250145606, Example 52)
Affinity DataIC50: 1.00E+3nMAssay Description:On the day of the assay, compounds were solubilized in DMSO and dispensed into a 384-well white Opti-plate (PerkinElmer, catalog #6007290) to generat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha(Human)
Arcus Biosciences

US Patent
LigandPNGBDBM738493(US20250145606, Example 52)
Affinity DataIC50: 1.00E+3nMAssay Description:On the day of the assay, compounds were solubilized in DMSO and dispensed into a 384-well white Opti-plate (PerkinElmer, catalog #6007290) to generat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Arcus Biosciences

US Patent
LigandPNGBDBM738493(US20250145606, Example 52)
Affinity DataIC50: 1.00E+3nMAssay Description:On the day of the assay, compounds were solubilized in DMSO and dispensed into a 384-well white Opti-plate (PerkinElmer, catalog #6007290) to generat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent