BDBM741062 N-(3-fluoro-4-((7-(4-mercaptobutoxy)-6-methoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl) cyclopropane-1,1-diformamide::US12304898, Example 7

SMILES COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCCS

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 741062   

TargetVascular endothelial growth factor receptor 2(Human)
Primegene (Beijing)

US Patent
LigandPNGBDBM741062(N-(3-fluoro-4-((7-(4-mercaptobutoxy)-6-methoxyquin...)
Affinity DataIC50: 57nMAssay Description:Detect compounds on VEGFR2 (KDR) by mobility shift assay. The initial test concentration of a compound was 1000 nM, 3 times dilution, 10 concentratio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent