BDBM741073 S-(7-((6-carbamoyl-4-(3-chloro-4-(3-cyclopropylurea)phenoxy)quinolin-7-yl)oxy)hexyl)thioacetate::US12304898, Example 86

SMILES CC(=O)SCCCCCCOc1cc2nccc(Oc3ccc(NC(=O)NC4CC4)c(Cl)c3)c2cc1C(N)=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 741073   

TargetVascular endothelial growth factor receptor 2(Human)
Primegene (Beijing)

US Patent
LigandPNGBDBM741073(S-(7-((6-carbamoyl-4-(3-chloro-4-(3-cyclopropylure...)
Affinity DataIC50: 2.60nMAssay Description:Detect compounds on VEGFR2 (KDR) by mobility shift assay. The initial test concentration of a compound was 1000 nM, 3 times dilution, 10 concentratio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent