BDBM744058 US20250170104, Compound 160

SMILES CC(C)CC(C(=O)NO)C(=O)Nc3ccc(Cn2cc(CNS(=O)(=O)c1ccc(F)cc1)nn2)cc3

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 744058   

TargetElastase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Helmholtz-Zentrum Fur Infektionsforschung

US Patent
LigandPNGBDBM744058(US20250170104, Compound 160)
Affinity DataIC50: 3.80nMAssay Description:Fluorescence intensity was measured for 60 min at 37° C. in black 384-well microtiter plates (Greiner BioOne, Kremsmünster, Austria) using a CLARIOst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/22/2025
Entry Details
US Patent

TargetElastase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Helmholtz-Zentrum Fur Infektionsforschung

US Patent
LigandPNGBDBM744058(US20250170104, Compound 160)
Affinity DataIC50: 3.80nMAssay Description:Fluorescence intensity was measured for 60 min at 37° C. in black 384-well microtiter plates (Greiner BioOne, Kremsmünster, Austria) using a CLARIOst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/22/2025
Entry Details
US Patent

TargetCytochrome c oxidase subunit 1(Human)
Helmholtz-Zentrum Fur Infektionsforschung

US Patent
LigandPNGBDBM744058(US20250170104, Compound 160)
Affinity DataIC50: 1.00E+5nMAssay Description:COX-1 Inhibitor Screening Assay Kit was purchased from Abcam. The assay was performed according to the guidelines of the manufacturer. Fluorescence s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/22/2025
Entry Details
US Patent

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Helmholtz-Zentrum Fur Infektionsforschung

US Patent
LigandPNGBDBM744058(US20250170104, Compound 160)
Affinity DataIC50: 1.00E+5nMAssay Description:The ADAM-17 (TACE) Inhibitor Screening Assay Kit was purchased from Sigma-Aldrich. The assay was performed according to the guidelines of the manufac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/22/2025
Entry Details
US Patent

TargetHistone deacetylase 8(Human)
Helmholtz-Zentrum Fur Infektionsforschung

US Patent
LigandPNGBDBM744058(US20250170104, Compound 160)
Affinity DataIC50: 1.00E+5nMAssay Description:HDAC3 and HDAC8 Inhibitor Screening Assay kits were purchased from Sigma-Aldrich. The assay was performed according to the guidelines of the manufact...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/22/2025
Entry Details
US Patent

TargetHistone deacetylase 3(Human)
Helmholtz-Zentrum Fur Infektionsforschung

US Patent
LigandPNGBDBM744058(US20250170104, Compound 160)
Affinity DataIC50: 1.00E+5nMAssay Description:HDAC3 and HDAC8 Inhibitor Screening Assay kits were purchased from Sigma-Aldrich. The assay was performed according to the guidelines of the manufact...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/22/2025
Entry Details
US Patent

TargetStromelysin-1 (MMP3)(Human)
Helmholtz-Zentrum Fur Infektionsforschung

US Patent
LigandPNGBDBM744058(US20250170104, Compound 160)
Affinity DataIC50: 1.00E+5nMAssay Description:MMPs-1, -2, -3, -7, -8 and -14 along with the SensoLyte 520 Generic MMP Activity Kit*Fluorimetric* were purchased from AnaSpec (Fremont, CA, USA). Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/22/2025
Entry Details
US Patent

Target72 kDa type IV collagenase (MMP2)(Human)
Helmholtz-Zentrum Fur Infektionsforschung

US Patent
LigandPNGBDBM744058(US20250170104, Compound 160)
Affinity DataIC50: 1.00E+5nMAssay Description:MMPs-1, -2, -3, -7, -8 and -14 along with the SensoLyte 520 Generic MMP Activity Kit*Fluorimetric* were purchased from AnaSpec (Fremont, CA, USA). Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/22/2025
Entry Details
US Patent

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Helmholtz-Zentrum Fur Infektionsforschung

US Patent
LigandPNGBDBM744058(US20250170104, Compound 160)
Affinity DataIC50: 1.00E+5nMAssay Description:MMPs-1, -2, -3, -7, -8 and -14 along with the SensoLyte 520 Generic MMP Activity Kit*Fluorimetric* were purchased from AnaSpec (Fremont, CA, USA). Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/22/2025
Entry Details
US Patent