BDBM75591 US20250382298, Compound 10

SMILES CS(=O)(=O)Nc1ccc(C(=O)Nc2cn3ccnc3c(N3CCC(F)(F)CC3)n2)c(N2CCC3(CC2)CC3)c1

InChI Key InChIKey=CWLGINURAYGZEZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 75591   

TargetKinesin-like protein KIF18A(Human)
Suzhou Genhouse Bio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 75591BDBM75591(US20250382298, Compound 10)
Affinity DataIC50: 25.7nMAssay Description:Broad Institute: Reversing Antifungal Drug Resistance Project ID: 2037 Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, Calcineurin, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent