BDBM75783 US20250382298, Compound 31

SMILES O=C(Nc1cn2ccnc2c(N2CCC3(CC2)CC3)n1)c1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2

InChI Key InChIKey=XMKINYMOEOBQGE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 75783   

TargetKinesin-like protein KIF18A(Human)
Suzhou Genhouse Bio Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 75783BDBM75783(US20250382298, Compound 31)
Affinity DataIC50: 55.3nMAssay Description:Broad Institute: Reversing Antifungal Drug Resistance Project ID: 2037 Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, Calcineurin, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent