BDBM766209 9-(4-hydroxybicyclo[2.2.1]heptan-1-yl)-7-methyl-2-((7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino)-7,9-dihydro-8H-purin-8-one ::US20250263753, Compound 1

SMILES Cc1cc2ncnn2cc1Nc1ncc2c(n1)n(C13CCC(O)(CC1)C3)c(=O)n2C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 766209   

LigandPNGBDBM766209(9-(4-hydroxybicyclo[2.2.1]heptan-1-yl)-7-methyl-2-...)
Affinity DataIC50: 0.0700nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.01% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO Required ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM766209(9-(4-hydroxybicyclo[2.2.1]heptan-1-yl)-7-methyl-2-...)
Affinity DataIC50: 88nMAssay Description:The assay detects kinase activity by antibody based HTRF assay. The GST-tagged p53 protein serves as substrate and Eu-labeled-antibody with specific ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM766209(9-(4-hydroxybicyclo[2.2.1]heptan-1-yl)-7-methyl-2-...)
Affinity DataIC50: 128nMAssay Description:A solution was prepared containing 0.2 nM Anti-HIS-Terbium (Cisbio, 64CUSTAZU), 3.7 nM designed-probe and 1.0 nM His-PIK3CA/PIK3R1 (p110 alpha/p85 al...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM766209(9-(4-hydroxybicyclo[2.2.1]heptan-1-yl)-7-methyl-2-...)
Affinity DataIC50: 658nMAssay Description:Step 1: Lipid kinases: Reaction Biology Corporation (RBC) currently offers lipid kinases in ADP-Glo formatStep 2: Assay Description Assay principle: ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM766209(9-(4-hydroxybicyclo[2.2.1]heptan-1-yl)-7-methyl-2-...)
Affinity DataIC50: 1.83E+3nMAssay Description:A solution was prepared containing 0.2 nM Anti-HIS-Terbium (Cisbio, 64CUSTAZU), 40 nM designed-probe and 1.0 nM His-PIK3CD/PIK3R1 (p110 delta/p85 alp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent