BDBM773914 US12427146, Compound 149

SMILES Cc1ncc(-c2nc(-c3cccc(NS(=O)(=O)c4c(Cl)cccc4Cl)c3F)c(-c3ccnc(NC4CC4)n3)s2)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 773914   

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandPNGBDBM773914(US12427146, Compound 149)
Affinity DataIC50: 4.5nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase Lck(Human)
Inventisbio Co.

US Patent
LigandPNGBDBM773914(US12427146, Compound 149)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent