BDBM792926 US12552795, Compound 3

SMILES C[C@@H](O)Cn1cc(-c2cc3c(N4CCN(c5ncc([C@@](C)(N)c6ccc(F)cc6)cn5)CC4)ncnn3c2)cn1

InChI Key InChIKey=OPOILSUUPUWPEK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 792926   

TargetMast/stem cell growth factor receptor Kit [D816V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 792926BDBM792926(US12552795, Compound 3)
Affinity DataKd: <0.300nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent

TargetPlatelet-derived growth factor receptor alpha [D842V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 792926BDBM792926(US12552795, Compound 3)
Affinity DataKd: <0.300nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 792926BDBM792926(US12552795, Compound 3)
Affinity DataKd: <10nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent

TargetCytochrome P450 3A4(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 792926BDBM792926(US12552795, Compound 3)
Affinity DataIC50: 3.99E+3nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent

TargetCytochrome P450 2C9(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 792926BDBM792926(US12552795, Compound 3)
Affinity DataIC50: 6.55E+3nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent

TargetCytochrome P450 2D6(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 792926BDBM792926(US12552795, Compound 3)
Affinity DataIC50: 1.00E+4nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent

TargetCytochrome P450 3A4(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 792926BDBM792926(US12552795, Compound 3)
Affinity DataIC50: 1.00E+4nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2026
Entry Details US Patent