BDBM799266 US12582655, Example Compound 1

SMILES Cc2nc(c1cnc(NC(C)C)n(C)c1=O)ccc2Oc4ccnc(c3cnn(C)c3)c4

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 799266   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Deciphera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 799266BDBM799266(US12582655, Example Compound 1)
Affinity DataIC50: 2.20nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Deciphera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 799266BDBM799266(US12582655, Example Compound 1)
Affinity DataKi:  864nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha(Human)
Deciphera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 799266BDBM799266(US12582655, Example Compound 1)
Affinity DataIC50: 2.50E+3nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Deciphera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 799266BDBM799266(US12582655, Example Compound 1)
Affinity DataIC50: 2.70E+3nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent