BDBM807860 N-(3-fluoro-4-((2-(1-methyl-1H- imidazol-4-yl)pyrazolo[1,5- a]pyrimidin-7-yl)oxy)phenyl)-1- (4-fluorophenyl)-5- (trifluoromethyl)-1H-pyrazole-4- carboxamide::US20260132158, Example 8

SMILES Cn1cnc(-c2cc3nccc(Oc4ccc(NC(=O)c5cnn(-c6ccc(F)cc6)c5C(F)(F)F)cc4F)n3n2)c1

InChI Key InChIKey=VGZLTELHYCFQIR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 807860   

TargetMacrophage-stimulating protein receptor(Human)
The Translational Genomics Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 807860BDBM807860(N-(3-fluoro-4-((2-(1-methyl-1H- imidazol-4-yl)pyra...)
Affinity DataIC50: 1.00E+3nMAssay Description:Kinase assay was done by following instructions from the kit. Briefly, a ten-point serial dilution of compound was prepared at 5× in assay buffer wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
The Translational Genomics Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 807860BDBM807860(N-(3-fluoro-4-((2-(1-methyl-1H- imidazol-4-yl)pyra...)
Affinity DataIC50: 3.25E+4nMAssay Description:Kinase assay was done by following instructions from the kit. Briefly, a ten point serial dilution of compound was prepared at 5× in assay buffer wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent