BDBM807869 N-(4-((2-amino-3-(1-methyl-1H- pyrazol-4-yl)pyridin-4-yl)oxy)- 3-fluorophenyl)-3-(4- fluorophenyl)isoxazole-5- carboxamide::US20260132158, Example 21

SMILES Cn1cc(-c2c(Oc3ccc(NC(=O)c4cc(-c5ccc(F)cc5)no4)cc3F)ccnc2N)cn1

InChI Key InChIKey=KESMMBUZURCOPZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 807869   

TargetMacrophage-stimulating protein receptor(Human)
The Translational Genomics Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 807869BDBM807869(N-(4-((2-amino-3-(1-methyl-1H- pyrazol-4-yl)pyridi...)
Affinity DataIC50: 3.00E+3nMAssay Description:Kinase assay was done by following instructions from the kit. Briefly, a ten-point serial dilution of compound was prepared at 5× in assay buffer wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
The Translational Genomics Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 807869BDBM807869(N-(4-((2-amino-3-(1-methyl-1H- pyrazol-4-yl)pyridi...)
Affinity DataIC50: 3.00E+3nMAssay Description:Kinase assay was done by following instructions from the kit. Briefly, a ten point serial dilution of compound was prepared at 5× in assay buffer wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent