BDBM807923 N-(4-((2-((3-(2-(4-Acryloylpiperazin-1-Yl)-2-Oxoethyl)Phenyl)Amino)-3-(Dimethylphosphoryl)Pyridin-4-Yl)Oxy)-3-Fluorophenyl)-1-(4-Fluorophenyl)-5-(Trifluoromethyl)-1H-Pyrazole-4-Carboxamide ::US20260132158, Example 38

SMILES C=CC(=O)N1CCCC(c2cccc(Nc3nccc(Oc4ccc(NC(=O)c5cnn(-c6ccc(F)cc6)c5C(F)(F)F)cc4F)n3)c2)C1

InChI Key InChIKey=VDFMGQLKNAHJTE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 807923   

TargetMacrophage-stimulating protein receptor(Human)
The Translational Genomics Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 807923BDBM807923(N-(4-((2-((3-(2-(4-Acryloylpiperazin-1-Yl)-2-Oxoet...)
Affinity DataIC50: 1.00E+3nMAssay Description:Kinase assay was done by following instructions from the kit. Briefly, a ten-point serial dilution of compound was prepared at 5× in assay buffer wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
The Translational Genomics Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 807923BDBM807923(N-(4-((2-((3-(2-(4-Acryloylpiperazin-1-Yl)-2-Oxoet...)
Affinity DataIC50: 3.25E+4nMAssay Description:Kinase assay was done by following instructions from the kit. Briefly, a ten point serial dilution of compound was prepared at 5× in assay buffer wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent