BDBM807982 N-(3-Fluoro-4-((2-((3-(2-(4-Propylpiperazin-1-Yl)Ethyl)Phenyl)Amino)Pyrimidin-4-Yl)Oxy)Phenyl)-1-(4-Fluorophenyl)-5-(Trifluoromethyl)-1H-Pyrazole-4-Carboxamide ::US20260132158, Example 43

SMILES C=CC(=O)N1CCN(CCc2cccc(Nc3nccc(Oc4ccc(NC(=O)c5cnn(-c6ccc(F)cc6)c5C(F)(F)F)cc4F)n3)c2)CC1

InChI Key InChIKey=GCPRMDMVHCDMIW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 807982   

TargetMacrophage-stimulating protein receptor(Human)
The Translational Genomics Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 807982BDBM807982(N-(3-Fluoro-4-((2-((3-(2-(4-Propylpiperazin-1-Yl)E...)
Affinity DataIC50: 1.00E+3nMAssay Description:Kinase assay was done by following instructions from the kit. Briefly, a ten-point serial dilution of compound was prepared at 5× in assay buffer wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
The Translational Genomics Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 807982BDBM807982(N-(3-Fluoro-4-((2-((3-(2-(4-Propylpiperazin-1-Yl)E...)
Affinity DataIC50: 1.00E+3nMAssay Description:Kinase assay was done by following instructions from the kit. Briefly, a ten point serial dilution of compound was prepared at 5× in assay buffer wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent